Evaluation of changes of intracranial blood flow after carotid artery stenting using digital subtraction angiography flow assessment

作     者：Hajime Wada Masato Saito Kyousuke Kamada 

作者机构：Department of NeurosurgeryAsahikawa Medical University 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2015年第7卷第2期

页      面：45-51页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

基　　金：Grants-in-Aid for Scientific Research [26242088  26670633  24390337] Funding Source: KAKEN 

主　　题：Intracranial blood flow Cerebral angiography Carotid artery stenting Single-photon emission computed tomography 

摘      要：AIM: To evaluate the changes of intracranial blood flow after carotid artery stenting(CAS), using the flow assessment application Flow-Insight, which was developed in our department.METHODS: Twenty patients treated by CAS participated in this study. We analyzed the change in concentration of the contrast media at the anterior-posterior and profile view image with the flow assessment application Flow-Insight. And we compared the results with N-isopropyl-p-[123I] iodoamphetamine-single-photon emission computed tomography(IMP SPECT) performed before and after the treatment. RESULTS: From this study, 200% of the parameter blood flow change in the post/pre-treatment is suggested as the critical line of the hyperperfusion syndrome arise. Although the observed blood flow increase in the digital subtraction angiography system did not strongly correlate with the rate of increase of SPECT, the Flow-Insight reflected the rate of change of the vessels well. However, for patients with reduced reserve blood flow before CAS, a highly elevated site was in agreement with the site analysis results. CONCLUSION: We concluded that the cerebral angiography flow assessment application was able to more finely reveal hyperperfusion regions in the brain after CAS compared to SPECT.