Belching,regurgitation,chest tightness and dyspnea:Not gastroesophageal reflux disease but asthma

作     者：Jing-Xi Zhang Xian-Bao Zhan Chong Bai Qiang Li 

作者机构：Department of Respiratory diseasesChanghai Hospitalthe Second Military Medical University Department of GastroenterologyChanghai Hospitalthe Second Military Medical University 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2015年第21卷第5期

页      面：1680-1683页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Asthma Gastroesophageal reflux disease 

摘      要：Belching is a common symptom of gastroesophageal reflux *** the symptoms are not relieved after anti-reflux treatment,another etiology should be ***,we report a case of a 43-yearold man who presented with belching,regurgitation,chest tightness and dyspnea for 18 mo,which became gradually more *** examination suggested superficial ***-four-houresophageal pH monitoring showed that the Demeester score was 11.4,in the normal ***-resolution manometry showed that integrated relaxation pressure and intrabolus pressure were higher than normal(20 mm Hg and 22.4 mm Hg,respectively),indicating gastroesophageal junction outflow tract *** function test showed severe obstructive ventilation dysfunction [forced expiratory volume in 1 second(FEV1)/forced vital capacity 32%,FEV1 was 1.21 L,occupying 35% predicted value after salbuterol inhalation],and positive bronchial dilation test(△FEV1 260 m L,△FEV1% 27%).Skin prick test showed Dermatophagoides farinae(++),house dust mite(++++),and shrimp protein(++).Fractional exhaled nitric oxide measurement was 76 *** the symptoms were alleviated completely and pulmonary function increased after combination therapy with corticosteroids and long-acting β*** asthma was eventually diagnosed by laboratory tests and the effect of anti-asthmatic treatment,therefore,physicians,especially the Gastrointestinal physicians,should pay attention to the belching symptoms of asthma.