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Preliminary study of a new pathological evolution-based clinical hepatolithiasis classification

Preliminary study of a new pathological evolution-based clinical hepatolithiasis classification

作     者:Fu-Bao Liu Xiao-Jun Yu Guo-Bing Wang Yi-Jun Zhao Kun Xie Fan Huang Jiang-Ming Cheng Xin-Rao Wu Chao-Jie Liang Xiao-Ping Geng 

作者机构:Department of Hepato-PancreatoBiliary Surgery the First Affiliated Hospital Anhui MedicalUniversity 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2015年第21卷第7期

页      面:2169-2177页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:Supported by Science and Technology Research Project of Anhui Province China No.12070403071 

主  题:Liver diseases Hepatolithiasis Clinical pathology 

摘      要:AIM:To investigate clinical features,treatment strategies and outcomes of patients with hepatolithiasis(HL)undergoing surgical treatment,using a new ***:Sixty-eight HL patients were hospitalized and treated surgically from August 2011 to December2012 and they were classified into four HL types according to pathological evolution of the *** four HL types included typeⅠprimary type(defined as no previous biliary tract surgery),typeⅡinflammatory type(with previous biliary tract surgery and cholangitis),typeⅢmass-forming type(HL complicated by hepatic mass-forming lesion),and typeⅣterminal type(with secondary biliary cirrhosis and resultant portal hypertension).The perioperative data including general information,imaging data,postoperative complications,and immediate and final stone clearance rate were obtained and ***:In all 68 patients,the proportion of HL typeⅠ-Ⅳwas 50%(34/68),36.8%(25/68),10.3%(7/68)and 2.8%(2/68),*** pain was the main clinical manifestation in typeⅠ(88.2%),fever was predominant in typeⅡ(52.0%),the malignancy rate in typeⅢwas high(71.4%),and portal hypertension and spleen enlargement were common in typeⅣ(2/2,100.0%).Liver resection rate for typesⅠ-Ⅲwas 79.4%,72.0%and 71.4%,*** overall incidence of postoperative complications was23.5%(16/68).There were no perioperative *** average length of hospital stay was 12.7±7.3 *** and final stone clearance rate was 73.5%(50/68)and 89.7%(61/68),***-nine of68 patients(86.8%)were followed-up for1 year after surgery,and 96.6%of these patients(57/59)had a good quality of life according to a criterion recommended for postoperative evaluation of quality of ***:The pathological evolution-based clinical classification of HL has a role in optimizingtreatment strategy,and patients can benefit from thisclassification when it is used properly.

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