Design optimization of highly sensitive LSPR enhanced surface plasmon resonance biosensors with nanoholes

作     者：吴斌 王庆康 

作者机构：National Key Laboratory of Micro/Nano Fabrication TechnologyKey Laboratory for Thin Film and Microfabrication Technology of Ministry of EducationResearch Institute of Micro/Nano Science and TechnologyShanghai Jiao Tong University 

出 版 物：《Chinese Optics Letters》 (中国光学快报（英文版）)

年 卷 期：2008年第6卷第5期

页      面：323-326页

核心收录：

学科分类：0808[工学-电气工程] 0809[工学-电子科学与技术（可授工学、理学学位）] 07[理学] 0805[工学-材料科学与工程（可授工学、理学学位）] 070204[理学-等离子体物理] 0702[理学-物理学] 

基　　金：the Nanotechnology Pro-grams of Science and Technology Commission of Shang-hai Municipality under Grant No.0652nm004 

主　　题：Biosensors Chemical sensors Curve fitting Electric fields Electromagnetic fields Gold Nanostructured materials Optical data storage Optimization Plasmons Resonance Sensitivity analysis Signal transduction 

摘      要：For breaking through the sensitivity limitation of conventional surface plasmon resonance （SPR） biosensors, novel highly sensitive SPR biosensors with Au nanopartieles and nanogratings enhancement have been proposed recently. But in practice, these structures have obvious disadvantages. In this study, a nanohole based sensitivity enhancement SPR biosensor is proposed and the influence of different structural parame- ters on the performance is investigated by using rigorous coupled wave analysis （RCWA）. Electromagnetic field distributions around the nanohole are also given out to directly explain the performance difference for various structural parameters. The results indicate that significant sensitivity increase is associated with localized surface plasmons （LSPs） excitation mediated by nanoholes. Except to outcome the weakness of other LSP based biosensors, larger resonance angle shift, reflectance amplitude, and sharper SPR curves＇ width are obtained simultaneously under optimized structural parameters.