Evaluation of cardiac function in patients with arrhythmogenic right ventricular cardiomyopathy by echocardiography

作     者：陈春晖 吴书林 张黔桓 费洪文 黄俊 薛玉梅 廖洪涛 方咸宏 詹贤章 

作者机构：Department of CardiologyGuangdong Provincial Cardiovascular InstituteGuangdong General HospitalGuangdong Academy of Medical Sciences Department of EchocardiologyGuangdong Provincial Cardiovascular InstituteGuangdong General HospitalGuangdong Academy of Medical Sciences 

出 版 物：《South China Journal of Cardiology》 (岭南心血管病杂志（英文版）)

年 卷 期：2013年第14卷第3期

页      面：164-170页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by Foundation of the Nature Science of Guangdong Province(No.10151008002000011) 

主　　题：arrhythmogenic right ventricular cardiomyopathy echocardiography doppler tissue imaging speckle tracking imaging 

摘      要：Background Arrhythmogenic right ventricular cardiomyopathy （ARVC） mainly performs local myocardial abnormal movements and tissue Doppler and spot tracking technique can accurately reflect myocardial movement. However, the technique is still rarely used in research of ARVC. Methods The study enrolled 28 ARVC patients and 28 normal controls. Right ventricular parameters were measured by two-dimensional echocardiography, tissue Doppler imaging, speckle tracking imaging in order to compare the difference between two groups. Results Morphological indices （right ventricular inflow tract inner diameter and right ventricular outflow tract inner diameter） and functional indices （right ventricular peak S＇, right ventricular E＇/ A＇ ratio, tricuspid annular plane systolic excursion, right ventricular fractional area change and right ventricular inferior and lateral wall longitudinal strain） showed significant difference between the ARVC group and control group. All the above-mentioned indices were analyzed by receiver operating characteristic curve （ROC curves）. Area under the curve （AUC） of right ventricular inferior wall longitudinal strain was the largest one （AUC = 0.94） with an optimal cutoff value of -19.5%. Conclusion Compared with two- dimensional echocardiography and tissue Doppler imaging, right ventricular inferior wall longitudinal strain is a more sensitive predictor for changes of ARVC.