生殖支原体:患病率、临床意义及传播途径

作     者：Anagrius C. Loré B. Jensen J.S. 李翠华 

作者机构：Department of Venereology Falu Lasarett SE- 791 82 Falun Sweden 

出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)

年 卷 期：2006年第2卷第4期

页      面：20-20页

学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

主　　题：生殖支原体 沙眼衣原体 性传播疾病 性伴 拭子 二重感染 横断面研究 无症状性 性接触 

摘      要：Objectives: To study the prevalence, symptoms and signs of Mycoplasma genitalium and Chlamydia trachomatis infections in STD clinic attendees and in partners of M genitalium infected patients. Methods: M genitalium and C trachomatis were detected by polymerase chain reaction from urethral and endocervical swab specimens in a cross sectional study among 445 female and 501 male STD clinic attendees. Partners of 26 female and 26 male M genitalium positive index patients were examined. Results: The prevalence of C trachomatis and M genitalium was 4% and 6.3% , respectively, among the women and 5.4% and 6% , respectively, among themen. Dual infections were uncommon. M genitalium was strongly associated with urethritis in bothmen and women and with cervicitis in women. Among M genitalium infected men, symptomatic urethritis was more common than asymptomatic urethritis. M genitalium and C trachomatis were not associated with symptoms of urethritis or cervicitis in women. Of 26 male partners of M genitalium positive female index patients, 38% were positive, and 77% of the negative partners had symptoms of urethritis. The concordance rate for 22 female partners of male index patients was 45% . For both men and women the M genitalium prevalence was significantly higher in partners of M genitalium positive index patients than in M genitalium negative index patients with urethritis and/or cervicitis. Conclusions: M genitalium is associated with urethritis in both men and women and with cervicitis in women. A high concordance rate was found among sexual partners of M genitalium infected patients, indicating that the infection is sexually transmitted.