Synthesis and evaluation of C-glycosides as hydrotropes and solubilizing agents

作     者：RANOUX Adeline LEMIEGRE Loc BENVEGNU Thierry 

作者机构：Ecole Nationale Supérieure de Chimie de RennesCNRS UMR 6226Université Européenne de Bretagne 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2010年第53卷第9期

页      面：1957-1962页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the ANRT (Association Nationale de la Recherche et de la Technologie) and the Armor Protéines Company for a grant to AR and for funding 

主　　题：C-glycoside amphiphiles Horner-Wadsworth-Emmons reaction Barbier allylation green chemistry hydrotropes 

摘      要：This work presents expeditious synthesis of C-glycoside amphiphiles in aqueous media from unprotected di-or mono-saccharides.A Horner-Wadsworth-Emmons/Michael addition/Barbier allylation sequence led to C-glycosides that exhibit hydrotropic *** hydrotropic and solubilizing properties of these homoallylic alcohols including a β-C-glycoside moiety as well as additional β-C-glycosidic ketones with a short(C7) alkyl chain are also described and compared with those of commercial O-glucoside references.