Endometrial Cancer Research Based on Gut Microbiomics and Metabolomics:An Analysis of Correlation and Differences

作     者：Dan Xu Fengqin Xue Ruifang Zhai Sanyuan Zhang Zhe Wang Peiyue Yu Dan Xu;Fengqin Xue;Ruifang Zhai;Sanyuan Zhang;Zhe Wang;Peiyue Yu

作者机构：Department of GynaecologyThe First People’s Hospital of DatongDatong 037008ShanxiChina Department of Shanxi Medical UniversityTaiyuan 030012ShanxiChina Department of GynaecologyThe First Hospital of Shanxi Medical UniversityTaiyuan 030001ShanxiChina 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2024年第37卷第10期

页      面：1204-1207页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：funded by the Fundamental Research Program of Shanxi Province(Grant number 202103021224394) 

主　　题：Metab Cancer quantities 

摘      要：Endometrial cancer(EC)is a malignant tumour that occurs in the epithelial cells of the endometrium and represents one of the most common malignancies involving the female reproductive system,with endometrioid adenocarcinoma as the most common *** recent years,with an increasingly aging society and the growing number of obese people,the incidence of EC is constantly rising,posing a serious threat to women’s *** studies have reported that the interruption of digestion and absorption caused by imbalance in intestinal microbiota may lead to conditions such as obesity,hypertension,diabetes,and hormone imbalance,which are all risk factors for ***,intestinal bacteria produce a series of metabolites during colonization and reproduction,which can rapidly respond to changes in the microenvironment of the *** in their types and quantities can serve as sensitive indicators of physiological and pathological changes in the *** with EC often suffer from metabolic diseases,which can lead to metabolic disorders involving carbohydrates,fats,and amino acid in their bodies.