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Biomedical and Environmental Sciences 2023年第3期36卷 289-294页

作者： LI Lei ZHENG Chong YE Jian Fang ZHU Kai ZHOU Yi Bing LIU Jia GAO Ming WU Yu Tian LIU Yong Ting LIU Li Ya LIN Ye LI Hai Chang ZHANG Quan GUO Hua Clinical Laboratory Guizhou Provincial Center for Disease Control and PreventionGuiyang 550004GuizhouChina Clinical Laboratory Guiyang Provincial Center for Disease Control and PreventionGuiyang 550002GuizhouChina

Numerous instances of poisoning caused by the ingestion of mushrooms are reported annually worldwide,with most mushroom poisoning deaths caused by the ingestion of toxic amanita *** is the main toxic component of aman... 详细信息

关键词： metab ani annually

metabotropic glutamate receptor 1 alpha:a unique receptor variant with variable implications for Alzheimer’s disease pathogenesis

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Neural Regeneration Research 2023年第10期18卷 2196-2197页

作者： Jason HY Yeung Andrea Kwakowsky Centre for Brain Research Department of Anatomy and Medical ImagingFaculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Pharmacology and Therapeutics School of MedicineGalway Neuroscience CentreOllscoil na Gaillimhe-University of GalwayGalwayIreland

Alzheimer’s disease (AD) is the leading neurodegenerative disorder *** this,there is minimal effective therapeutics proven to reduce or prevent the progression of this *** is the main excitatory neurotransmitter with... 详细信息

关键词： Alzheimer metab pathogenesis

Changes in Urinary metabolomics of Female Kashin-Beck Disease Patients in Qinghai-Tibet Plateau,China

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Biomedical and Environmental Sciences 2023年第6期36卷 537-541页

作者： LI Qiang ZHOU Xin XUE Hong Mei WANG Jian Ling LI Ji Quan ZHAO Yan Mei CHAO Jie CHEN Yang Yang XU Li Qing ZHAO Zhi Jun WANG Li Hua Qinghai Institute for Endemic Disease Prevention and Control Xining 810021QinghaiChina Medical College Qinghai universityXining 810010QinghaiChina The Center for Endemic Disease Control Chinese Center for Disease Control and PreventionHarbin Medical UniversityHarbin 150081HeilongjiangChina

Kashin-Beck disease(KBD)is a chronic,endemic,degenerative osteoarthropathic condition that is predominantly found in China's *** is a progressive disease,and the signs and symptoms become more severe in adulthood owing to the continuous development of lesions in the joint cartilage[1].Although childhood KBD has largely been controlled,adult KBD is an important health concern in rural ***,in the last century,many adult KBD patients still remain during serious epidemics.

关键词： metab Plateau mainland

metabolomic profiling provides new insights into blood-brain barrier regulation

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Neural Regeneration Research 2021年第9期16卷 1786-1787页

作者： Sheng-Fu Huang Omolara O.Ogunshola Institute for Veterinary Physiology Zurich Center for Integrative Human PhysiologyUniversity of ZurichSwitzerland

Early blood-brain barrier(BBB) disturbance contributes to many different neurological diseases including Alzheimer 's disease, Parkinson's disease and stroke, particularly in the etiology and early stages(Abbott et al... 详细信息

关键词： metab al. diseases

metabolon:a novel cellular structure that regulates specific metabolic pathways

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Cancer Communications 2021年第6期41卷 439-441页

作者： Tian Tian Jun Fan Shannon Elisabeth Elf Department of Medical Biochemistry and Molecular Biology School of MedicineJinan UniversityGuangzhouGuangdong 510632P.R.China The Ben May Department for Cancer Research the University of ChicagoChicagoIllinois 60637USA

Tumor cells exhibit several metabolic abnormalities,such as uptake disorders of glucose and amino acids,increased nutrient consumption rates,use of glycolysis/tricarboxylic acid(TCA)cycle intermediates for biosynthesis and NADPH production,and increased demand for nitrogen sources[1].As an increasing understanding of cancer cell metabolism has been gained in recent years,the metabolic changes and molecular mechanisms associated with tumors in different tumor stages have been gradually revealed.

关键词： metabolism metab ed.

Endocrinology and metabolism

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China Medical Abstracts(Internal Medicine) 2022年第3期39卷 153-159页

2022258 Comparison of criteria for metabolically healthy overweight/obesity in Shanghai Changfeng ***(吴琪),et *** Endocrinol,Zhongshan Hosp,Fudan metab Dis Instit,Human Phenome Instit,Fudan Univ,Shanghai *** J Intern Med 2022;61(7):*** Toestablish a moresuitableand practicable criterion of metabolically healthy overweight/obesity(MHO/O)in Chinese,a comparison study on different criteria of MHO/O was conducted in subjects aged over 45-year-old in Shanghai Changfeng Community.

关键词： obesity metab

PQBP1:A New Player in metabotropic Glutamate Receptor Signaling and Synaptic Plasticity

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Neuroscience Bulletin 2021年第11期37卷 1637-1638页

作者： Li-Da Su Ying Shen Neuroscience Care Unit Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou310009China Department of Physiology Zhejiang University School of MedicineHangzhou310058China

Group 1 metabotropic glutamate receptors(Gp1 mGluRs),comprising mGluR1 and mGluR5,are predominantly located at postsynaptic ***1 mGluRs induce the activation of phospholipase C-γ.

关键词： mGluR5 metab Receptor

Long-term Di-(2-ethylhexyl) phthalate Exposure Disturbs the Lipid metabolism Profiles and Hepatic Enzymes in Male Rats:A UPLC-MS-based Serum metabolomics Analysis

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Biomedical and Environmental Sciences 2021年第11期34卷 920-925页

作者： DONG Xin Wen WU Wei Dong YAO San Qiao ZHANG Yun Bo WANG Cheng WU Hao Yu NA Xiao Lin Department of Environmental and Occupational Health School of Public HealthXinxiang Medical UniversityXinxiang 453003HenanChina Department of Environmental Hygiene Public Health CollegeHarbin Medical UniversityHarbin 150086HeilongjiangChina

In recent years,many investigations have indicated that environmental endocrine disruptors(EEDs)may accelerate the development of obesity[1].One kind of EEDs,di-(2-ethylhexyl)phthalate(DEHP),is ubiquitous in natural e... 详细信息

关键词： Lipid metab Serum

metabolism and Endocrinology

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China Medical Abstracts(Internal Medicine) 2009年第4期26卷 200-206页

2009415 Serum adipocyte-fatty acid binding protein:an important marker of abdominal obesity in *** Lan,et *** Endocrinol,Changhai Hosp,2nd Milit Med Univ,Shanghai *** J Endocrinol metab 2009;25(4):391-393. Objective To analyze the association of adipocyte-fatty acid binding protein (A-FABP) levels with abdominal obesity in *** Total 174 high-school students (101 male and 73 female)aged

关键词： obesity metab adolescent adipocyte FABP leptin obese Serum waist circumference

metabolism and Endocrinology

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China Medical Abstracts(Internal Medicine) 2010年第1期27卷 17-24页