Revisiting normal perfusion pressure breakthrough in light of hemorrhage-induced vasospasm

作     者：Matthew D Alexander E Sander Connolly Philip M Meyers 

作者机构：Department of Diagnostic ImagingSanta Clara Valley Medical CenterSan JoseCA 95128United States Department of Neurological SurgeryColumbia UniversityCollege of Physicians and SurgeonsNew YorkNY 10032United States Department of RadiologyColumbia UniversityCollege of Physicians and SurgeonsNew YorkNY 10032United States 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2010年第2卷第6期

页      面：230-232页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：Arteriovenous malformation Autoregulation Normal perfusion pressure breakthrough Subarachnoid hemorrhage Vasospasm 

摘      要：Cerebral arteriovenous malformations(AVMs) have abnormally enlarged arteries and veins prone to spontaneous *** following surgical excision of a cerebral AVM,even normal brain tissue surrounding the lesion is subject to hemorrhage,a phenomenon termed normal perfusion pressure breakthrough(NPPB) *** to this theory,arteries supplying cerebral AVMs become dilated and lose their capacity to dilate or constrict to autoregulate *** after removal of a cerebral AVM,excessive blood pressure in these arterial feeders can cause normal brain tissue to ***,this theory remains *** present a patient with a cerebral AVM that demonstrated cerebrovascular reactivity and argues against an assumption underlying the theory of NPPB syndrome.