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Erosive esophagitis associated with metabolic syndrome,impaired liver function, and dyslipidemia

Erosive esophagitis associated with metabolic syndrome,impaired liver function, and dyslipidemia

作     者:Song-Seng Loke Kuender D Yang Kuang-Den Chen Jung-Fu Chen 

作者机构:Department of Family Medicine Kaohsiung Chang Gung Memorial Hospital Chang Gung University College of Medicine Department of Medical Research Show Chwan Memorial Hospital Center for Translational Research in Biomedical Science Kaohsiung Chang Gung Memorial Hospital Division of Endocrinology and Metabolism Department of Internal Medicine Kaohsiung Chang Gung Memorial Hospital 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2013年第19卷第35期

页      面:5883-5888页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Erosive esophagitis Metabolic syndrome Central obesity Abnormal liver function Dyslipidemia 

摘      要:AIM:To investigate whether erosive esophagitis is correlated with metabolic syndrome and its components,abnormal liver function,and lipoprotein ***:We conducted a cross-sectional,case control study of subjects who underwent upper endoscopy during a health examination at the Health Management and Evaluation Center of a tertiary medical care facility located in Southern *** syndrome components,body mass index(BMI),liver function,dyslipidemia,and cardiovascular risk factors,as defined by the ratio of total cholesterol to high-density lipoprotein cholesterol(HDL-C),and the ratio of low-density lipoprotein cholesterol to HDL-C were compared betweenindividuals with and without erosive *** factors for erosive esophagitis were evaluated by multivariate logistic ***:Erosive esophagitis was diagnosed in 507of 5015 subjects who were individually age and sex matched to 507 esophagitis-free control *** patients with erosive esophagitis,BMI,waist circumference,blood pressure,fasting plasma glucose,triglyceride levels,aspartate aminotransferase,alanine aminotransferase,the ratio of total cholesterol to HDL-C,and the ratio of low-density lipoprotein cholesterol to HDL-C were significantly higher and HDL-C was significantly lower compared to patients without erosive esophagitis(all P5(OR=1.45;95%CI:1.06-1.97),and aspartate aminotransferase(OR=1.59;95%CI:1.08-2.34)were significantly associated with erosive ***:Metabolic syndrome,impaired liver function,and a higher ratio of total cholesterol to HDL-C were associated with erosive esophagitis.

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