MRI versus 64-row MDCT for diagnosis of hepatocellular carcinoma

作     者：Michael Bernhard Pitton Roman Kloeckner Sascha Herber Gerd Otto Karl Friedrich Kreitner Christoph Dueber 

作者机构：Department of Diagnostic and Interventional RadiologyJohannes Gutenberg-University Department of Transplantation and Hepatobili-opancreatic SurgeryUniversity of Mainz 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2009年第15卷第48期

页      面：6044-6051页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：磁共振成像 螺旋CT 肝癌 诊断 

摘      要：AIM:To compare the diagnostic capability of multidetector computed tomography(MDCT) and magnetic resonance imaging(MRI) for the detection of hepatocellular carcinoma(HCC) tumour nodules and their effect on patient ***:A total of 28 patients(25 male,3 female,mean age 67±10.8 years) with biopsy-proven HCC were investigated with 64-row MDCT(slice 3 mm native,arterial and portal-venous phase,120 mL Iomeprol,4 mL/s,delay by bolus trigger) and MRI(T1fs fl2d TE/ TR 2.72/129 ms,T2tse TE/TR 102/4000 ms,5-phase dynamic contrast-enhanced T1fs fl3d TE/TR 1.56/4.6,Gadolinium-DTPA,slice 4 mm).Consensus reading of both modalities was used as *** nodules were analyzed with respect to number,size,and ***:In total,162 tumour nodules were detected by consensus *** detected signifi cantly more tumour nodules(159 vs 123,P20 *** missed 2 nodules ≤10 mm and 1 nodule ≤15 *** MRI,nodule diameters were greater than on CT(29.2±25.1 mm,range 5-140 mm vs 24.1±22.7 mm,range 4-129 mm,P0.005).In 2 patients,MDCT showed only unilobar tumour spread,whereas MRI revealed additional nodules in the contralateral *** of these nodules could have changed the therapeutic ***:Contrast-enhanced MRI is superior to 64-row MDCT for the detection of HCC *** should be allocated to interventional or operative treatment according to a dedicated MRI-protocol.