Family case of achalasia cardia: Case report and review of literature

作     者：Yulia Viktorovna Evsyutina Alexander Sergeevich Trukhmanov Vladimir Trophimovich Ivashkin 

作者机构：Department of Internal Disease Propaedeutics Gastroenterology and Hepatology Sechenov First Moscow State Medical University 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第4期

页      面：1114-1118页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Achalasia cardia Dysphagia Regurgitation Gene poly 

摘      要：Achalasia cardia is an idiopathic disease that occurs as a result of inflammation and degeneration of myenteric plexi leading to the loss of postganglionic inhibitory neurons required for relaxation of the lower esophageal sphincter and peristalsis of the *** main symptoms of achalasia are dysphagia,regurgitation,chest pain and weight *** present,there are three main hypotheses regarding etiology of achalasia cardia which are under consideration,these are genetic,infectious and *** theory is one of the most widely *** report given below represents an inheritable case of achalasia cardia which was not diagnosed for a long time in an 81-year-old woman and her 58-year-old daughter.