致敏离体豚鼠气管横向或螺旋条对腺苷的收缩反应:上皮的作用
Responses to adenosine of isolated transverse or spiral strips of sensitized guinea pig trachea: role of epithelium作者机构:Cardiff University 英国
出 版 物:《Acta Pharmacologica Sinica》 (中国药理学报(英文版))
年 卷 期:2001年第22卷第6期
页 面:5-11页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学]
摘 要:INTRODUCTION The loss of , or damage to, the epithelial layer hasbeen shown to alter the responsiveness of airway smooth muscle preparations to a variety of agents. These effectshave been related to the epithelium serving as a diffusionbarrier, as an uptake site, or a source of epithelium-derived relaxant factor (EpDRF). Removal of theepithelium for example by ozone exposure causes airway