ERCP在诊断造血干细胞移植受体胰胆管病变中的作用

作     者：Alnusair M.M. De Magalhaes-Silverman M. Silverman W.B. 成虹 

作者机构：Division of Gastroenterology and HepatologyUniversity of Iowa Hospital and ClinicIowa CityIAUnited States Dr. 

出 版 物：《世界核心医学期刊文摘（胃肠病学分册）》 (Core Journals in Gastroenterology)

年 卷 期：2006年第2卷第9期

页      面：36-37页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100215[医学-康复医学与理疗学] 10[医学] 

主　　题：异体造血干细胞移植 ERCP检查 胰胆管病变 诊断价值 受体 肝外胆管梗阻 自体造血干细胞移植 胆管并发症 

摘      要：Background:Patients undergoing hematopoietic stem cell transplant may develop pancreatico-biliary complications that may require *** to their immunocompromised state,these patients may be at higher risk of procedure-related ***:To determine the role of ERCP in the diagnosis and treatment of patients who have undergone hematopoietic stem cell transplant and the patients’clinical ***:Retrospective analy-sis of patients with hematopoietic stem cell transplant who underwent ERCP from 1997 to 2004 evaluating ERCP indications,diagnosis,therapeutic interventions,and ***:Tertiary referral ***:Of the 16 patients identified,9 were female,15 had had allogeneic hematopoietic stem cell transplant,and 1 had an autologous hematopoietic stem cell ***-six ERCP procedures were performed in the 16 *** ERCP findings included:extra hepatic bile duct obstruction in 12 patients,of which 7 had biliary *** obstruction due to infiltration from graft versus host disease was seen in 3 of 12 patients,benign bile duct stricture in 1 of 12,and ampullary obstruction in the setting of a periampullary diverticulum in 1 of *** ERCP findings in the remaining 4 patients included:intrahepatic bile duct compression due to metastatic disease in 1 of 16 patients,bile duct leak in 1 of 16,pancreatic duct stone in 1 of 16,and normal ERCP in 1 of *** occurred in 4 patients:mild pancreatitis(1),mild bleeding(1),cholangitis due to late stent occlusion(1),and intermittent bradycardia(1).There were no ERCP-related ***:Single-center ***:In patients with hematopoietic stem cell transplant,bile duct lithiasis was the most common finding at ERCP,followed by obstructive ampullary tissue infiltration due to graft versus host *** yielded clinically relevant information in this particular group of patients.