Emergence of target waves in neuronal networks due to diverse forcing currents

作     者：MA Jun WANG ChunNi YING HePing WU Ying CHU RunTong 

作者机构：Department of PhysicsLanzhou University of Technology Department of PhysicsZhejiang University School of AerospaceXi'an Jiaotong University 

出 版 物：《Science China(Physics,Mechanics & Astronomy)》 (中国科学：物理学、力学、天文学（英文版）)

年 卷 期：2013年第56卷第6期

页      面：1126-1138页

核心收录：

学科分类：0711[理学-系统科学] 07[理学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0704[理学-天文学] 

基　　金：supported by the National Nature Science Foundation of China (Grant Nos. 11265008 and 11272242) 

主　　题：神经元网络 电流 准周期信号 离子通道 局部区域 边界条件 信道噪声 电活动 

摘      要：The electric activities of neurons could be changed when ion channel block occurs in the neurons.External forcing currents with diversity are imposed on the regular network of Hodgkin-Huxley(HH) neuron,and target waves are induced to occupy the network.The forcing current I1 is imposed on neurons in a local region with m 0 ×m 0 nodes in the network,neurons in other nodes are imposed with another forcing current I2.Target wave could be developed to occupy the network when the gradient forcing current(I1-I2) exceeds certain threshold,and the formation of target wave is independent of the selection of boundary condition.It is also found that the developed target wave can decrease the negative effect of ion channel block and suppress the spiral wave,and thus channel noise is also considered.The potential mechanism of formation of target wave could be that the gradient forcing current(I1-I2) generates quasi-periodical signal in local area,and the propagation of quasi-periodical signal induces target-like wave due to mutual coupling among neurons in the network.