Studies on surgical methods for sporadic micromedullary thyroid carcinoma
作者机构：Department of Head and Neck SurgerySun Yat-sen University Cancer Center Gansu HospitalLanzhouGansuChina
出 版 物：《Oncology and Translational Medicine》 (肿瘤学与转化医学（英文版）)
年 卷 期：2024年第10卷第4期
页 面：184-189页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by a grant from the Gansu Provincial Nature Foundation Project(no.23URRA2346)
主 题：Thyroid papillary carcinoma Surgery Calcitonin Carcinoembryonic antigen
摘 要：Background:To observe the changes in serum calcitonin levels after application of different surgical methods for primary medullary thyroid microcarcinoma(MTMC)and explore a more reasonable surgical ***:A retrospective analysis of 36 patients with MTMC,16 in group A and 20 in group B,was *** group A,tumors were single and confined to the thyroid lobe,and thyroid lobectomy with isthmusectomy was *** group B,tumors were in the isthmus or invaded the thyroid gland,or there were multiple foci in bilateral lobes,and patients with primary foci underwent total *** median follow-up time was 3.6 *** and pathological characteristics and changes in serum calcitonin(CTn)and carcinoembryonic antigen levels after the surgery were compared between the 2 ***:The difference in the biochemical cure rate after surgery was statistically significant between patients with preoperative serum calcitonin levels0.05).One recurrence and metastasis were observed in each group after ***:After performing different surgical methods for the primary foci of MTMC,the changes in serum calcitonin and carcinoembryonic antigen levels are *** for patients with single foci confined to the thyroid lobe without lateral cervical lymph node metastasis and with serum calcitonin levels150 pg/mL,the unilateral thyroid lobectomy with isthmectomy can achieve the same therapeutic effect and biochemical cure rate as total thyroidectomy.
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