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嗜铬细胞瘤与颅内出血

Intracranial haemorrhage associated with phaeochromocytoma (Fren)

作     者:Gelis A. Pelissier J. Blard J.M. Pagès M 王晓琳 

作者机构:Servicede Neurologie A Centre Gui de Chauliac 80 avenue Fliche34295 Montpellier Cedex 5 France 

出 版 物:《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals:Clinical Neurology)

年 卷 期:2005年第1卷第4期

页      面:50-51页

学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主  题:嗜铬细胞瘤 颅内出血 阵发性高血压 双侧肾上腺 肾上腺瘤 脑动脉瘤 蛛网膜下腔出血 瘤体切除 儿茶酚 影像学 

摘      要:Introduction. Pheochromocytoma is rarely disclosed by intracranial hemorrhage. We report two cases. Observation, The first 26- year- old patient developed subarachnoid hemorrhage due to a ruptured aneurysm of the middle cerebral artery. The second patient, aged 44 years, had a temporal hematoma. Diagnosis was suggested in both patients by hypertension and elevated urinary catecholamines and confirmed by imaging and MIBG scintigraphy. Adrenal gland tumors, on both glands in the first patient and on the right gland in the second were successfully removed; cranial hypertension totally regressed. Von Hippel Lindau disease was diagnosed by molecular genetics in the first patient. Paroxysmal hypertension could explain the brain hemorrhage in the first patient and may have favored aneurysmal rupture in the second. Conclusion. The relationships between pheochromocytoma and cerebral aneurysm are discussed.

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