Synthetic fungal melanin UV absorbers

作     者：Chao Wang Rong Zhang Jianhua Zhang Xueqian Zhang Hengjie Zhang Huan Cao Zhen Yang Yiwen Li 

作者机构：College of Polymer Science and EngineeringState Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065China Department of RadiologyHuaxi MR Research CenterFunctional and Molecular Imaging Key Laboratory of Sichuan ProvinceNational Clinical Research Center for GeriatricsWest China HospitalSichuan UniversityChengdu 610041China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2024年第67卷第9期

页      面：3098-3110页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 07[理学] 0817[工学-化学工程与技术] 08[工学] 070205[理学-凝聚态物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0703[理学-化学] 0702[理学-物理学] 

基　　金：supported by National Natural Science Foundation of China(52225311) Sichuan Science and Technology Program(2024NSFSC1018) China Postdoctoral Science Foundation(2024M752208) Postdoctoral Fellowship Program of CPSF(GZC20241108) the Fundamental Research Funds for Central Universities 

主　　题：melanin artificial allomelanin nanoparticles green synthesis UV absorption antibacterial 

摘      要：Agents with robust ultraviolet(UV)absorption capabilities play a vital role in safeguarding organisms and inorganic materials from UV ***,the synthetic procedures towards these UV absorbers are usually lengthy and complicated,accompanied by undesirable side reactions and the generation of toxic *** nature,allomelanin,a class of melanins variant found in melanized fungi near the Chernobyl nuclear power plant,plays crucial roles in the cell wall of melanized fungi,offering resistance to harsh external environments and promising UV resistance ***,allomelanin can be rapidly biosynthesized via the polymerization of 1,8-dihydroxynaphthalene in presence of enzymes in *** by this,we report here a green enzymatic polymerization strategy to efficiently and eco-friendly synthesize polydihydroxynaphthalene(PDHN)-based artificial allomelanin nanoparticles(NPs)with interesting *** calculations and experimental results demonstrated that the PDHN NPs exhibited excellent UVabsorption capacity,surpassing another widely used artificial melanin,polydopamine(PDA).Moreover,the light absorption mechanism of PDHN NPs was systematically elucidated for the first ***,the PDHN NPs were incorporated with polyvinyl alcohol(PVA)to create an anti-aging composite film with significantly enhanced UV shielding *** potential of these composite films in safeguarding plants from UV damage was meticulously ***,these PDHN NPs were first found to produce hydroxyl radicals(·OH)under UV irradiation,offering antibacterial properties that expand their potential applications.