Frequency Selectivity Behaviour in the Auditory Midbrain： Implications of Model Study

作     者：匡神兵 王嘉赋 曾婷 

作者机构：Department of Physical Science and Technology Wuhan University of Technology Wuhan 430070 

出 版 物：《Chinese Physics Letters》 (中国物理快报（英文版）)

年 卷 期：2006年第23卷第12期

页      面：3380-3383页

核心收录：

学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 071003[理学-生理学] 10[医学] 

基　　金：国家教育部重点项目 

主　　题：VENTRAL COCHLEAR NUCLEUS POTASSIUM CURRENTS NEURONS PREFERENCES VERTEBRATES MECHANISMS RESPONSES SYSTEMS PITCH 

摘      要：By numerical simulations on frequency dependence of the spiking threshold, i.e. on the critical amplitude of periodic stimulus, for a neuron to fire, we find that bushy cells in the cochlear nuclear exhibit frequency selec- tivity behaviour. However, the selective frequency band of a bushy cell is far away from that of the preferred spectral range in human and mammal auditory perception. The mechanism underlying this neural activity is also discussed. Further studies show that the ion channel densities have little impact on the selective frequency band of bushy cells. These findings suggest that the neuronal behaviour of frequency selectivity in bushy cells at both the single cell and population levels may be not functionally relevant to frequency discrimination. Our results may reveal a neural hint to the reconsideration on the busily cell functional role in auditory information processing of sound frequency.