房颤患者中充血性心力衰竭的发生率和死亡风险:一项超过20年的社区研究

作     者：Miyasaka Y. Barnes M.E. Gersh B.J. T.S.M.Tsang 苏畅 

作者机构：Division of Cardiovascular Disease and Internal MedicineMayo Clinic200 First Street SWRochesterMN 55905United States 

出 版 物：《世界核心医学期刊文摘（心脏病学分册）》 (Digest of the World Core Medical Journals(Cardiology))

年 卷 期：2006年第2卷第9期

页      面：23-24页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：充血性心力衰竭 死亡风险 房颤患者 发生率 社区研究 时间变化 平均年龄 CHF 

摘      要：Aims: We sought to determine whether the incidence of and survival following congestive heart failure(CHF) in patients with atrial fibrillation(AF) have changed over time. Methods and results: Olmsted County, Minnesota residents diagnosed with first AF during 1980-2000 were identified and followed in medical records to 2004. The trends of incidence and survival of CHF over time were assessed. Of the 3288 subjects(mean age 71±15 years) diagnosed with first AF and without CHF prior to or at AF diagnosis, 790(24%) developed a first CHF during a mean follow-up of 6.1±5.2 years(unadjusted incidence, 44 per 1000 person years). Age-and sex-adjusted CHF incidence was unrelated to calendar year of AF diagnosis(P=0.86). The age-and sex-adjusted mortality risk following CHF was higher than that in patients without CHF(hazard ratio 3.4, 95%confidence interval 3.1-3.8, P 0.0001). There were no detectable changes over time with respect to the absolute(P=0.94) or the relative(P=0.68) mortality risk after CHF diagnosis. Conclusion: In this study spanning two decades, there appeared to have been no significant reduction in terms of the incidence and mortality risk of CHF following first AF diagnosis.