Esophagogastroduodenoscopy-assisted bowel preparation for colonoscopy

作     者：Robert L Barclay 

作者机构：Rockford Gastroenterology AssociatesRockfordIL 61107-5078United States 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2013年第5卷第3期

页      面：95-101页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Colonoscopy Bowel preparation Tolerability Esophagogastroduodenoscopy-assisted 

摘      要：AIM:To compare the quality and tolerance of esophag ogastroduodenoscopy(EGD)-assisted and conventional split-dose polyethylene glycol electrolyte solution for inpatient ***:The study was a randomized controlled trial in hospitalized *** patients undergoing colonoscopy the day following EGD for evaluation of gastrointestinal(GI) bleeding or other *** randomized to either EGD-assisted bowel prep [2 L polyethylene glycol(PEG) administered endoscopically into distal duodenum at time of EGD,plus 1 L PEG orally the following day] or conventional-PEG(2 L PEG orally the evening prior and 1 L PEG orally the following day).The main outcome measurements are bowel preparation quality and patient tolerance of bowel ***:Forty-two patients randomized to EGD-assisted bowel prep and 40 patients to *** mean ± SD preparation quality was superior for EGD-PEG(4.1 ± 2.8) vs conventional-PEG(6.5 ± 3.1;P = 0.0005).Seventy-four percent of patients rated EGDPEG as easy or slightly difficult to tolerate compared to 46% for standard-PEG(P = 0.0133).Mean EGD-procedural time was greater for EGD-assisted subject(24 ± 10 min) compared to conventional-PEG prep subjects(15 ± 7 min;P 0.0001).Conscious sedation requirements did not differ between *** were no significant prep-related adverse events in either ***:In selected hospitalized patients,compared to a conventional split-dose regimen,use of EGD to administer the majority of PEG solution improves patient tolerance and quality of bowel preparation for colonoscopy.