巴西扩张性心肌病患者乳糜泻的患病率
Celiac disease prevalence in Brazilian dilated cardiomyopathy patients作者机构:Rua Dr.Alexandre Gutierrez no.863CuritibaParanáBrazil Dr.
出 版 物:《世界核心医学期刊文摘(胃肠病学分册)》 (Core Journals in Gastroenterology)
年 卷 期:2006年第2卷第12期
页 面:7-7页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题:心肌病患者 乳糜泻 抗肌内膜抗体 心脏移植 消化道内镜检查 自身免疫性疾病 间接免疫荧光法 抗体检测
摘 要:Celiac disease(CD) is a permanent condition of gluten intolerance and a number of autoimmune diseases have been associated with *** the past few years,a relation between CD and dilated cardiomyopathy(CM) was described in Europe and United *** aim of this study was to evaluate the prevalence of CD among south Brazilian precardiac transplant patients with advanced CM.A total of 74 patients on a list for heart transplantation were evaluated for the presence *** presence of anti-endomisial antibody(IgA-EmA) was determined by indirect immunofluorescence and for the anti-transglutaminase antibody(IgA anti-h-tTG) by *** positive patients were submitted to upper endoscopy with intestinal *** individuals(2.63%) were positive for IgA-EmA and 5(6.75%) for IgA anti-h-tTG;1(1.35%) had both tests *** confirmation of CD occurred only in the IgA-EmA positive *** conclusion,data from the present study allows recommend the screening for CD in patients with CM using IgA-EmA test as the method of choice.