Environmentally friendly polylysine gauze dressing for an innovative antimicrobial approach to infected wound management
作者机构：State Key Laboratory of Oral Diseases National Clinical Research Center for Oral Diseases West China College of Stomatology Sichuan University College of Biomass Science and Engineering Key Laboratory of Biomass Fibers for Medical Care in Textile Industry Sichuan University Division of Thyroid Surgery Department of General Surgery Laboratory of Thyroid and Parathyroid Disease Frontiers Science Center for Disease-Related Molecular Network West China Hospital Sichuan University
出 版 物：《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期：2024年第35卷第10期
页 面：335-340页
核心收录：
学科分类：0821[工学-纺织科学与工程] 08[工学] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0703[理学-化学] 082102[工学-纺织材料与纺织品设计]
基 金：supported by the National Natural Science Foundation of China (Nos. 82370977, 52073186) Medical Science and Technology Project of Sichuan Provincial Health Commission (No. 21PJ059) Science and Technology Application Fundamental Project of Sichuan Province (No. 2022YFS0124) Funding for Distinguished Young Scholars of Sichuan Province (No. 23NSFJQ0001) Strategic Cooperation Projects of Yi Bin City and Sichuan University (No. 2020CDYB-6)
主 题：Antimicrobial Environmentally friendly Infected wound management Modified cotton dressing Polylysine
摘 要：Infections frequently occur after skin injuries, posing a significant challenge in current clinical care. Frequently changing dressings to minimize wound infections and adhesions results in large amounts of medical waste. Therefore, developing environmentally friendly multifunctional dressings has considerable application and translational significance. This study aimed to prepare a wound dressing with favorable antimicrobial properties and biosafety by grafting a natural antimicrobial peptide, polylysine, onto a traditional cotton textile dressing. The cotton textile dressing offers excellent moisture absorption and softness, while polylysine provides excellent biocompatibility, a broad antimicrobial spectrum, and high stability. Furthermore, both materials are natural and biodegradable, making them ideal for environmentally friendly wound dressings.
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