Preparation of TiO_(2) Nano-Flower Coating on Ti Substrates with Good Physical Sterilization Effect and Biocompatibility
作者机构：Shanxi Key Laboratory of Biomedical Metal MaterialsCollege of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan030024China College of Safety and Emergency Management EngineeringTaiyuan University of TechnologyTaiyuan030024China
出 版 物：《Acta Metallurgica Sinica(English Letters)》 (金属学报（英文版）)
年 卷 期：2024年第37卷第9期
页 面：1581-1589页
核心收录：
学科分类：0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 0817[工学-化学工程与技术] 08[工学] 100102[医学-免疫学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学]
基 金：jointly supported by the Four“Batches”Innovation Project of Invigorating Medical through Science and Technology of Shanxi Province(2022XM12) the Central Leading Science and Technology Development Foundation of Shanxi Province(YDZJSX2021A019) the Key Research and Development Program of Shanxi Province(202102130501007) the Natural Science Foundation of Shanxi Province(202103021223102,202203021222127)
主 题：Anodization Biocompatibility Physical sterilization TiO_(2)nano-flower
摘 要：We report a facile solution method to form titanium oxide(TiO_(2))nano-flower structure on the titanium(Ti)substrates for realizing good physical sterilization and *** first prepare TiO_(2) nanotubes(NT)with a diameter of about 80-100 nm and a length of about 5μm on Ti substrates by anodization,which is utilized as ***,we employ immersion treatment in different concentrations of phosphoric acid solution at 75℃ for 5 h to realize the transformation from TiO_(2) NT to TiO_(2) nano-flower *** addition,we studied the effects of phosphoric acid concentration(1 wt%,2.5 wt%,5 wt% and 10 wt%)on the TiO_(2) nano-flower structure,and the antibacterial properties and biocompatibility of the TiO_(2) nano-flower *** results show that TiO_(2) nano-flower structure become larger and thicker with the increase in the phosphoric acid concentration,and the thickness of the coating can reach 6.88μ***,the TiO_(2) nano-flower structure shows good physical sterilization effect,especially for the TiO_(2) nano-flower structure formed in 10 wt%H^(3)PO_(4) solution,the antibacterial rate can reach 95%.In addition,the TiO_(2) nano-flower structure have no toxicity to the osteoblasts and support cell growth.
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