Targeting neutrophil subsets is a novel approach for myocardial ischemia-reperfusion injury

作     者：Valerii Chereshnev Valerii Chereshnev

作者机构：Institute of Immunology and PhysiologyUral Branch of the Russian Academy of ScienceEkaterinburg 620049Russia 

出 版 物：《Science Bulletin》 (科学通报（英文版）)

年 卷 期：2024年第69卷第18期

页      面：2814-2815页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：neutrophil ischemia 

摘      要：Recently,in their 2024 study,Dong et al.[1]revealed the pivotal role of neutrophils in the immune response of myocardial ischemia-reperfusion injury(MIRI)via single-cell RNA sequencing(sc RNA-seq),and identified the existence and function of a novel neutrophil subset with repair phenotype,which participates in the cardio-protection of MIRI by regulating the polarization of macrophages via *** finding not only deepens our understanding of cellular interactions within MIRI but also opens new therapeutic avenues.