Quality Standard of Tibetan Medicine Nardostachys jatamansi Herba Based on"An Integrated Plant but Multi-purpose"

作     者：Hairong ZHONG Yuebu HAILAI Shaoshan ZHANG Wenbing LI Yuan LIU 

作者机构：College of PharmacySichuan College of Traditional Chinese MedicineMianyang 621000China Sichuan Provincial Qiang-Yi Medicinal Resources Protection and Utilization Technology and Engineering LaboratoryChengdu 610225China Key Laboratory of Protection and Utilization of Ethnic Medicinal Resources on Qinghai-Tibet PlateauState Ethnic Affairs CommissionChengdu 610225China Southwest Minzu UniversityChengdu 610225China 

出 版 物：《Medicinal Plant》 (药用植物：英文版)

年 卷 期：2024年第15卷第3期

页      面：16-22页

学科分类：1006[医学-中西医结合] 1005[医学-中医学] 100513[医学-民族医学(含：藏医学、蒙医学等)] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by National Key R&D Plan Project (2018YFC1708005) Application Foundation Project of Sichuan Provincial Department of Science and Technology (20YYJC3299) Special Fund for Basic Scientific Research Business Expenses of Central Universities of Southwest Minzu University (2020NGD01) 

主　　题：Nardostachys jatamansi Herba Chlorogenic acid 3 5-O-dicaffeoylquinic acid Fingerprint Quality standard Resource utilization 

摘      要：[Objectives]To establish the quality standard of Nardostachys jatamansi Herba.[Methods]The characters and microscopical identification of *** Herba were carried *** contents of moisture,total ash,acid-insoluble ash and extract were determined according to the relevant methods of the Chinese Pharmacopoeia(2020 edition).Using chlorogenic acid and 3,5-O-dicaffeoylquinic acid as quality control indexes,TLC and HPLC methods were established for qualitative and quantitative determination,and HPLC fingerprints were established.[Results]The characteristics of character identification,microscopic identification and thin layer identification were *** moisture content ranged from 2.7%to 7.8%,with an average value of 5.4%.The total ash content ranged from 6.7%to 16.2%,with an average of 11.0%.The acid-insoluble ash content ranged from 0.7%to 8.5%,with an average of 3.6%.Extractives content ranged from 20.9%to 34.4%,with an average of 29.7%.Chlorogenic acid content was between 0.45%and 1.30%,with an average value of 0.77%.The content of 3,5-O-dicaffeoylquinic acid ranged from 0.18%to 0.58%,with an average of 0.31%.The similarity of each batch was between 0.930 and 0.994,indicating that the quality of medicinal materials from different producing areas was stable.[Conclusions]The quality standard of *** Herba was established,which could provide quality control basis for rational,comprehensive and efficient utilization of *** *** and clinical use.