Systemic lupus erythematosus with diffuse alveolar hemorrhage

作     者：Rongxiu Huo Xinxiang Huang Jinying Lin 

作者机构：Department of Rheumatology and ImmunologyGuangxi Academy of Medical SciencesThe People’s Hospital of Guangxi Zhuang Autonomous RegionNanningGuangxi 530016China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2023年第136卷第23期

页      面：2883-2885页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：erythematosus lupus organs damage 

摘      要：To the Editor:Systemic lupus erythematosus(SLE)is an autoimmune disease characterized by the production of various autoantibodies.Disease prevalence is 20 to 70 per 100,000 among adults,and 1.89 to 25.7 per 100,000 among children.[1,2]The pathogenesis of SLE is associated with immune disorders,especially involving the activation of B and T cells,which can lead to abnormal antibodies with nuclear and cytosolic antigens from apoptotic cells of the immune complexes(ICs)removing the damaged cells,and excessive activation of the complement system,thus causing damage to target organs,such as the kidneys and lungs.