Menstrual irregularity,pregnancy outcomes,and birth outcomes in patients with systemic lupus erythematosus of childbearing age in China:a multicenter cross-sectional study

作     者：Yuke Hou Jiayang Jin Liang Luo Yuchao Zhong Zhe Peng Ziyi Song Chun Li Xuewu Zhang 

作者机构：Department of Rheumatology and ImmunologyPeking University People’s HospitalBeijing 100044China Department of Chinese MedicineChongqing Yubei People’s HospitalChongqing 401120China Department of Rheumatology and ImmunologyPeking University Shenzhen HospitalShenzhenGuangdong 518036China Center of Reproductive MedicinePeking University People’s HospitalBeijing 100044China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2023年第136卷第23期

页      面：2886-2888页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基　　金：Beijing Natural Science Foundation(No.7192211) China International Medical Foundation(No.Z-2018-40-2101) 

主　　题：patients sectional birth 

摘      要：To the Editor:Systemic lupus erythematosus(SLE)is an autoimmune disease that tends to affect females of childbearing age.There are nearly 4 million people in China currently suffering from SLE,which can cause multiple organ damage in its early stages and seriously affect patients’quality of life.[1-3]Menstrual disorders are common in SLE patients and vary from heavy menstrual bleeding to amenorrhea.The etiology of menstrual irregularities includes the disease activity itself,glucocorticoids(GCs)treatment,and the use of some immunosuppressants.[4]This multicenter,cross-sectional,web-based observational study investigated menstrual irregularity,pregnancy outcomes,and birth outcomes on SLE patients across China.The research was approved by the Ethics Committee of Peking University People’s Hospital,China(No.2019PHB253-01).The patients were informed that consent was implied with completion of the questionnaire,and the process was anonymous and voluntary.