Enhanced in-vitro degradation resistance and cytocompatibility of a thermomechanically processed novel Mg alloy:Insights into the role of microstructural attributes

作     者：Darothi Bairagi Santanu Mandal Mangal Roy Manas Paliwal Sumantra Mandal 

作者机构：Department of Metallurgical and Materials EngineeringIndian Institute of TechnologyKharagpur 721302India 

出 版 物：《Journal of Magnesium and Alloys》 (镁合金学报（英文）)

年 卷 期：2024年第12卷第2期

页      面：700-725页

核心收录：

学科分类：0806[工学-冶金工程] 08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程（可授工学、理学学位）] 

主　　题：Magnesium alloy Microstructure Corrosion Electrochemical impedance spectroscopy X-ray photoelectron spectroscopy Cytotoxicity 

摘      要：The role of microstructural features on in-vitro degradation and surface film development of a thermomechanically processed Mg-4Zn-0.5Ca-0.8Mn alloy has been investigated employing electrochemical studies,scanning electron microscopy and X-ray photoelectron *** specimen forged at 523 K temperature developed a coarse unimodal microstructure consisting of basal oriented grains,whereas the specimens forged at 623 K and 723 K temperatures exhibited bimodal microstructures containing randomly oriented fine grains and basal oriented coarse *** bimodal microstructures exerted higher resistance to corrosion compared to the unimodal microstructure in presence of a protective surface *** optimum size distribution of fine and coarse grains as well as the prevalence of basal oriented grains led to the lowest anodic current density in the specimen forged at 623 *** morphology of Ca_(2)Mg_(6)Zn_(3)precipitates governed the cathodic kinetics by controlling the anode to cathode surface area *** the specimen forged at 723 K comprised comparatively lower fraction of precipitates than at 623 K,the mesh-like precipitate morphology increased the effective cathodic surface area,leading to enhanced localised corrosion in the former *** microstructural features developed at 623 K forging temperature formed a well-protective surface film with lower Mg(OH)_(2)to MgO ratio,exhibiting distinctly high polarization resistance and superior cytocompatibility in terms of cell-proliferation and cell-differentiation.