Development trends of etiological research contents and methods of noncommunicable diseases

作     者：Dafang Chen Yujia Ma Han Xiao Zeyu Yan 

作者机构：Department of Epidemiology and BiostatisticsSchool of Public HealthPeking UniversityBeijingChina Key Laboratory of Epidemiology of Major Diseases(Peking University)Ministry of EducationPeking UniversityBeijingChina 

出 版 物：《Health Care Science》 (科学医疗（英文）)

年 卷 期：2023年第2卷第5期

页      面：352-357页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：National Natural Science Foundation of China Grant/Award Numbers:81872692 82073642 

主　　题：noncommunicable diseases multimorbidity etiology systems perspective network life course 

摘      要：1|BACKGROUND Noncommunicable diseases(NCDs)are a significant public concern,greatly impacting the economic and social development in *** 2019,NCDs accounted for a staggering 88.5%of total deaths in China,with cardiovas-cular diseases,cancer,chronic respiratory diseases,and diabetes—the four major chronic diseases—contributing to a premature mortality rate of 16.5%[1].The complexity of NCDs arises from the involvement of multiple genetic and environmental factors that interact in intricate *** complexity is characterized by a multitude of interactions among genes,proteins,and metabolic path-ways throughout the various stages of life.