Exploring the diversity of microbes and natural products from fungus-growing termite tripartite symbiosis

作     者：Muhammad Shoaib Ruining Bai Shuai Li Yan Xie Yulong Shen Jinfeng Ni Muhammad Shoaib;Ruining Bai;Shuai Li;Yan Xie;Yulong Shen;Jinfeng Ni

作者机构：State Key Laboratory of Microbial TechnologyMicrobial Technology InstituteShandong UniversityQingdao 266237China Institute of Health SciencesIslamabad Campus.Khyber Medical UniversityPeshawar KPK25120 Pakistan CRISPR and Archaea Biology Research CentreMicrobial Technology Institute and State Key Laboratory of Microbial TechnologyShandong UniversityQingdao 266237China 

出 版 物：《Engineering Microbiology》 (工程微生物学（英文）)

年 卷 期：2024年第4卷第1期

页      面：66-80页

学科分类：0710[理学-生物学] 07[理学] 09[农学] 

基　　金：supported by grants from the National Natural Science Foundation of China(31970119 31272370) 

主　　题：Fungus-growing termite Tripartite symbiosis Diversity Termitomyces Microbes 

摘      要：The fungus-growing termite is considered a distinct ecological niche because it involves a tripartite symbiosis between the termite host,gut microflora,and the in vitro fungus Termitomyces,which has led to the expansion of highly organized and complex societies among termite *** symbiosis in fungus-growing termites may promote unique microbes with distinctive metabolic pathways that may serve as valuable resources for developing novel antimicrobial therapeutic *** research on complex tripartite symbioses has revealed a plethora of previously unknown natural products that may have ecological roles in signaling,communication,or defense *** products produced by symbionts may act as crucial intermediaries between termites and their pathogens by providing direct protection through their biological ***,we review the state-of-the-art research on both microbes and natural products originated from fungus-growing termite tripartite symbiosis,highlighting the diversity of microbes and the uniqueness of natural product classes and their ***,we emphasize future research prospects on fungus-growing termite related microorganisms,with a particular focus on their potential roles in bioactive product discovery。