Use of eschar swab DNA to diagnose Rickettsia conorii subspecies conorii infection in Crimea:A case report

作     者：Emine E.Alieva Muniver T.Gafarova Eugene I.Bondarenko Igor A.Dovgan Irina I.Osiptchuk Marina E.Eremeeva Emine E.Alieva;Muniver T.Gafarova;Eugene I.Bondarenko;Igor A.Dovgan;Irina I.Osiptchuk;Marina E.Eremeeva

作者机构：Federal State Budgetary Institution‘N.I.Pirogov Saki Military Clinical Sanatorium’Ministry of Defense of RussiaSaki 296500Russia S.I.Georgievsky Medical Academy(Academic Unit)V.I.Vernadsky Crimean Federal UniversitySimferopol 295051Russia Vector-BestNovosibirsk 630117Russia Saki Regional HospitalSaki 296500Russia Jiann-Ping Hsu College of Public HealthGeorgia Southern UniversityStatesboroGA 30458USA 

出 版 物：《Infectious Medicine》 (感染医学（英文）)

年 卷 期：2023年第2卷第4期

页      面：338-342页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：NCBI GenBank 

主　　题：Eschar Mediterranean spotted fever PCR Rickettsia conorii Swab 

摘      要：Mediterranean spotted fever(MSF)has been diagnosed clinically in the Crimean Peninsula since the *** describe the recent illness of an elderly patient from Crimea who had developed a classic triad of MSF symptoms consisting of fever,maculopapular rash,and *** diagnosis of rickettsiosis was confirmed using real-time PCR and sequencing of 4 Rickettsia protein *** strain causing clinical illness was characterized as Rickettsia conorii subspecies conorii Malish *** report corroborates the utility of eschar swab material as a source of DNA for PCR-based diagnostics that enables timely patient treatment and management.