Glucocorticoid reduction induced chorea in pediatric-onset systemic lupus erythematosus:A case report

作     者：Yan-Qiu Xu Miao Wang Ying Zhang 

作者机构：Department of RheumatologyChongqing Hospital of Traditional Chinese MedicineChongqing 400021China 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2023年第11卷第32期

页      面：7872-7875页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100214[医学-肿瘤学] 10[医学] 

基　　金：This study was conducted with the approval of the ethics committee of Chongqing Hospital of Traditional Chinese Medicine(approval No.2023-GAKY-KS-XYQ).The patient gave explicit informed consent to report her clinical case 

主　　题：Glucocorticoid Chorea Pediatric systemic lupus erythematosus Case report 

摘      要：BACKGROUND Pediatric-onset systemic lupus erythematosus(SLE)is typically more severe than adult-onset SLE,with a higher incidence of nervous system *** is a relatively rare neurological complication reported in 2.4%-7%of SLE *** particular,chorea induced by glucocorticoid dose reduction is even ***,we report the case of a girl with SLE,who developed chorea during the process of glucocorticoid therapy *** SUMMARY We describe a 14-year-old girl who was diagnosed with *** was treated with methylprednisolone and rituximab,and her symptoms *** the second day after the methylprednisolone dose was reduced according to the treatment guidelines,the patient developed *** condition improved after adjusting her glucocorticoid *** This case is a reminder that extra attention to chorea is required in SLE patients during glucocorticoid dose reduction.