Risk Factors for Diabetes and Cardiovascular Complications in the Chinese Population

作     者：Chun Dou Dong Liu Tiange Wang 

作者机构：Department of Endocrine and Metabolic DiseasesShanghai Institute of Endocrine and Metabolic DiseasesRuijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Shanghai National Clinical Research Center for Metabolic DiseasesKey Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR ChinaShanghai Key Laboratory for Endocrine TumorRuijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina. 

出 版 物：《China CDC weekly》 (中国疾病预防控制中心周报（英文）)

年 卷 期：2023年第5卷第45期

页      面：1017-1021页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the grants from the National Natural Science Foundation of China(82022011,81970706) the“Shanghai Municipal Education Commission–Gaofeng Clinical Medicine Grant Support”from Shanghai Jiao Tong University School of Medicine(20171901 Round 2) the Innovative Research Team of High-Level Local Universities in Shanghai 

主　　题：obesity sized consequence 

摘      要：Type 2 diabetes,a major noncommunicable disease,is typified by hyperglycemia,which stems from insulin resistance and dysfunction of pancreaticβ-cells(1).Prior multi-ethnic studies hypothesized that type 2 diabetes among Caucasians was primarily driven by insulin resistance,whereas in East Asians,it was predominantly a consequence ofβ-cell dysfunction(2).Apart from the apparent genetic variations,obesity has been identified as the main factor responsible for the pathophysiological differences in diabetes between Caucasians and East Asians(3).Notably,China has seen a considerable increase in obesity cases in congruence with substantial changes in lifestyle and urbanization over the last four *** a recent population-based national cohort study,we showed that insulin resistance,rather thanβ-cell dysfunction,had a significant role in the pathological progression of diabetes within the Chinese population(1).This correlation was particularly pronounced among obese adults(1).