Synthesis and Antibacterial Properties of ZIF-8/Ag-Modified Titanium Alloy
作者机构：Key Laboratory of Automobile Materials of MOEDepartment of Materials Science and EngineeringJilin UniversityChangchun 130022China State Key Laboratory for Materials Processing and Die and Mould TechnologySchool of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhan 430074China
出 版 物：《Journal of Bionic Engineering》 (仿生工程学报（英文版）)
年 卷 期：2022年第19卷第2期
页 面：507-515页
核心收录：
学科分类：08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0811[工学-控制科学与工程]
基 金：supported by the National Natural Science Foundation of China(No.51627805).
主 题：Zeolitic imidazolate framework-8 Antibacterial Osseointegration Surface modifcatio
摘 要：The loosening of implant due to bacterial infection brings great difficulties to the implantation of bionic titanium devices.In this study,the Zeolitic Imidazolate Framework 8(ZIF-8)and silver ions were added to the surface of titanium alloy to obtain a uniform coating,which has nice biological activity and antibacterial property.The material structure characterizations,such as X-ray diffraction(XRD),scanning electron microscope(SEM),X-ray photoelectron spectroscopy(XPS),proved that titanium is successfully modified with ZIF-8 and silver ions.It has micro-and nano-level characteristics,rough porous morphology,and excellent apatite inducing ability.The water contact angle experiment shows that the addition of ZIF-8 greatly increases the hydrophilicity of material,which provides conditions for the attachment of osteoblasts.The polarization curve obtained from the electrochemical test proves that the addition of ZIF-8 coating improves the corrosion resistance of titanium.The release of silver ion has a strong growth inhibitory effect on E.coli,and exhibits excellent antibacterial properties.Therefore,the preparation of ZIF-8/Ag coatings on 3D printed titanium provides a new option for the development of orthopedic implants.
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