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文献详情 >Drug-coated balloons for the t... 收藏

Drug-coated balloons for the treatment of ostial left anterior descending or ostial left circumflex artery lesions:a patientlevel propensity score-matched analysis

作     者:Liang PAN Wen-Jie LU Zhan-Ying HAN San-Cong PAN Xi WANG Ying-Guang SHAN Meng PENG Xiao-Fei QIN Guo-Ju SUN Pei-Sheng ZHANG Jian-Zeng DONG Chun-Guang QIU Liang PAN;Wen-Jie LU;Zhan-Ying HAN;San-Cong PAN;Xi WANG;Ying-Guang SHAN;Meng PENG;Xiao-Fei QIN;Guo-Ju SUN;Pei-Sheng ZHANG;Jian-Zeng DONG;Chun-Guang QIU

作者机构:Department of Cardiovascular Medicinethe First Affiliated Hospital of Zhengzhou UniversityZhengzhouChina Department of CardiologyJincheng People’s HospitalJinchengChina Department of Cardiologythe Fifth Affiliated Hospital of Zhengzhou UniversityZhengzhouChina 

出 版 物:《Journal of Geriatric Cardiology》 (老年心脏病学杂志(英文版))

年 卷 期:2023年第20卷第10期

页      面:716-727,I0001-I0005页

核心收录:

学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基  金:supported by the Medical Science and Technique Research Plan of He’nan Province(Provincial and Ministerial Co-construction Project)(SB201901027) 

主  题:lesions balloon treatment 

摘      要:BACKGROUND Controversy exists as to the optimal treatment approach for ostial left anterior descending(LAD)or ostial left circumflex artery(LCx)***-coated balloons(DCB)may overcome some of the limitations of drug-eluting stents(DES).Therefore,we investigated the security and feasibility of the DCB policy in patients with ostial LAD or ostial LCx lesions,and compared it with the conventional DES-only *** We retrospectively enrolled patients with de novo ostial lesions in the LAD or LCx who underwent interventional *** were categorized into two groups based on their treatment approach:the DCB group and the DES *** treatment strategies in the DCB group involved the use of either DCB-only or hybrid strategies,whereas the DES group utilized crossover or precise stenting ***-year target lesion revascularization was the primary endpoint,while the rates of major adverse cardiovascular events,cardiac death,target vessel myocardial infarction,and vessel thrombosis were the secondary *** propensity score matching,we assembled a cohort with comparable baseline *** ensure result analysis reliability,we conducted sensitivity analyses,including interaction,and stratified *** Among the 397 eligible patients,6.25%of patients who were planned to undergo DCB underwent DES.A total of 108 patients in each group had comparable propensity scores and were included in the ***-year target lesion revascularization occurred in 5 patients(4.90%)and 16 patients(16.33%)in the DCB group and the DES group,respectively(odds ratio=0.264,95%CI:0.093–0.752,P=0.008).Compared with the DES group,the DCB group demonstrated a lower major adverse cardiovascular events rate(7.84%vs.19.39%,P=0.017).However,differences with regard to cardiac death,non-periprocedural target vessel myocardial infarction,and definite or probable vessel thrombosis between the groups were *** The utilization of

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