Incidence and Outcomes of Surgical Site Infections after Adult Cardiac Surgery: A Single-Center Experience

作     者：Ibraheem H. Alharbi Hasan I. Sandogji Ahmed M. Shabaan Khaled M. Sayed Bilal A. Rahmani Mohamed A. Elmetwali Nouf A. Lami Thikra S. Alkhalaf Shyelene T. Utuanis Ayman R. Abdelrehim Ibraheem H. Alharbi;Hasan I. Sandogji;Ahmed M. Shabaan;Khaled M. Sayed;Bilal A. Rahmani;Mohamed A. Elmetwali;Nouf A. Lami;Thikra S. Alkhalaf;Shyelene T. Utuanis;Ayman R. Abdelrehim

作者机构：Cardiology Department Madinah Cardiac Center Madinah Saudi Arabia Cardiac Surgery Department Madinah Cardiac Center Madinah Saudi Arabia Cardiothoracic Surgery Department Faculty of Medicine Suez Canal University Ismaïlia Egypt Infection Prevention and Control Department Madinah Cardiac Center Madinah Saudi Arabia Clinical Nurse Unit Cardiac Surgery Department Madinah Cardiac Center Madinah Saudi Arabia Cardiothoracic Surgery Department Faculty of Medicine Menoufia University Menoufia Egypt 

出 版 物：《World Journal of Cardiovascular Diseases》 (心血管病（英文）)

年 卷 期：2023年第13卷第11期

页      面：764-779页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Surgical Site Infection Cardiac Surgery Mortality Risk Factors Outcomes 

摘      要：Background: Surgical site infections (SSIs) remain a challenging medical problem, especially in cardiac surgery patients. There is a lack of studies evaluating the rate of and outcomes of SSIs following cardiac surgeries in Saudi Arabia. Aims: This study aimed to determine the incidence of SSIs after adult cardiac surgeries that were done in Madinah Cardiac Center, Saudi Arabia. Further, to identify the outcomes and risk factors contributing to death among surgical site infection patients. Methods: This was a 6-year, single-center, retrospective cohort study that included 93 consecutive patients who underwent adult cardiac surgery between August 2016 and August 2022. All adult patients aged 18 years or older who had clinical evidence of postoperative surgical wound infection were included. Preoperative, operative, and postoperative data (early and late) were collected from medical records. Microbiological culture reports and clinical outcomes were also recorded. Results: The study revealed a 9.1% (93/1021) incidence rate of SSIs. Of the 93 patients with SSIs, 60 had superficial incisional infections and 33 had deep infections with incidence rates of 5.9% and 3.2%, respectively. In-hospital mortality due to SSI was recorded in 4 out of 93 patients with an incidence rate of 4.3%. There was a significant association between the in-hospital mortality and the type of SSIs (p = 0.014). All non-survivors had deep SSIs. The type of cardiac surgery also showed a significant association with the in-hospital mortality (p = 0.017). Furthermore, the median duration of antibiotic administration was significantly longer in the non-survivors than in the survivors (72.5 vs 17, respectively, p Conclusions: In conclusion, the incidence of surgical wound infections following cardiac surgery is not low (9.1%);of which 3.2% were deep infections. The in-hospital mortality rate after treatment of SSIs was fortunately low (4.3%), and all non-survivors had deep SSIs. The non- survivors showe