The lack of association between different LDL-C levels and oxidized LDL in patients with type 2 diabetes

作     者：Soghra Rabizadeh Seyed Arsalan Seyedi Seyed Ali Nabipoorashrafi Maryamossadat Omidvar Siahkalmahalleh Amirhossein Yadegar Fatemeh Mohammadi Armin Rajab Alireza Esteghamati Manouchehr Nakhjavani Soghra Rabizadeh;Seyed Arsalan Seyedi;Seyed Ali Nabipoorashrafi;Maryamossadat Omidvar Siahkalmahalleh;Amirhossein Yadegar;Fatemeh Mohammadi;Armin Rajab;Alireza Esteghamati;Manouchehr Nakhjavani

作者机构：Endocrinology and Metabolism Research Center(EMRC)Vali-Asr HospitalSchool of MedicineTehran University of Medical SciencesTehranIran 

出 版 物：《Chronic Diseases and Translational Medicine》 (慢性疾病与转化医学(英文版))

年 卷 期：2023年第9卷第4期

页      面：329-335页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：National Institute for Medical Research Development Grant/Award Number:996168 

主　　题：atherosclerosis diabetes mellitus lipids lipoproteins low-density lipoprotein oxidized LDL 

摘      要：Background:High concentrations of low-density lipoprotein cholesterol(LDL-C)have been a known risk factor for cardiovascular ***,the role of oxidized LDL(ox-LDL)in forming atherosclerosis plaque has been ***,it has not yet been proven that atherogenic LDL-C byproducts like ox-LDL will decrease by keeping the LDL levels at the desired *** study aimed to examine the relationship between LDL-C and ox-LDL in different LDL-C values in patients with type 2 diabetes(T2D).Methods:In this cross-sectional study,347 patients with T2D who received statins were ***-C values were defined into four groups as LDLC100 mg/dL in patients with ***,the revealed association of ox-LDL with TG level and TG/HDL ratio may be considered in the clinic.