Selenium and human nervous system

作     者：Wenqiang Ding Shuang Wang Jiaxiang Gu Lei Yu Wenqiang Ding;Shuang Wang;Jiaxiang Gu;Lei Yu

作者机构：Institute of Translational MedicineMedical CollegeYangzhou UniversityYangzhou 225001China Department of Hand and FootClinical Medical CollegeYangzhou UniversityYangzhou 225001China School of Chemistry and Chemical EngineeringYangzhou UniversityYangzhou 225002China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2023年第34卷第7期

页      面：11-16页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071006[理学-神经生物学] 0703[理学-化学] 

基　　金：Jiangsu Provincial Six Talent Peaks Project (No. XCL090) the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD) for support support of the fund of the joint-laboratory of Shanghai Dingya Pharmaceutical Chemical Technology Co., Ltd. with Yangzhou University (2022-2027)。 

主　　题：Selenium Nervous system Selenoprotein Nano-selenium Plumbism Brain function 

摘      要：Selenium plays various biological functions in the form of selenoprotein in human body. Brain is one of the most abundant organs of selenoprotein, which plays an important role in maintaining brain redox homeostasis, signal transduction pathway regulation and neuroimmune regulation. Yet, nano-selenium have attracted much attention for their high bioavailability and low toxicity. Nano-selenium are of great application potential in field of biomedical nervous system. Recently, investigation on selenoprotein and nano-selenium has gradually become a new hotspot for the important functions of selenium in human nervous system. In this article, we wish to review recent progresses and give a perspective.