Trousseau's syndrome in a patient with advanced stage gastric cancer

作     者：Tai-Long Chien Kung-Ming Rau Wen-Jung Chung Wei-Chen Tai Shih-Ho Wang Yi-Chun Chiu Keng-Liang Wu Yeh-Pin Chou Chia-Che Wu Yen-Hao Chen Seng-Kee Chuah 

作者机构：Division of GastroenterologyDepartment of Internal MedicinePin-Tung An-Tai Hospital Division of OncologyDepartment of Internal MedicineKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Division of CardiologyDepartment of Internal MedicineKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Division of HepatogastroenterologyDepartment of Internal MedicineKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Division of General SurgeryDepartment of SurgeryKaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2015年第21卷第34期

页      面：10049-10053页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Gastric cancer Arterial thrombotic events Troussea 

摘      要：Patients with cancer are at high risk for thrombotic events,which are known collectively as Trousseau s syndrome. Herein,we report a 66-year-old male patient who was diagnosed with terminal stage gastric cancer and liver metastasis and who had an initial clinical presentation of upper gastrointestinal bleeding. Acute ischemia of the left lower leg that resulted in gangrenous changes occurred during admission. Subsequent angiography of the left lower limb was then performed. This procedure revealed arterial thrombosis of the left common iliac artery with extension to the external iliac artery,the left common iliac artery,the posterior tibial artery,and the peroneal artery,which were occluded by thrombi. Aspiration of the thrombi demonstrated that these were not tumor thrombi. The interesting aspect of our case was that the disease it presented as arterial thrombotic events,which may correlate with gastric adenocarcinoma. In summary,we suggested that the unexplained thrombotic events might be one of the initial presentations of occult malignancy and that thromboprophylaxis should always be considered.