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Current status and future perspectives for the treatment of resectable locally advanced esophagogastric junction cancer:A narrative review

作     者:Yoshiaki Shoji Kazuo Koyanagi Kohei Kanamori Kohei Tajima Mika Ogimi Kentaro Yatabe Miho Yamamoto Akihito Kazuno Kazuhito Nabeshima Kenji Nakamura Takayuki Nishi Masaki Mori 

作者机构:Department of Gastroenterological SurgeryTokai University School of MedicineIsehara 259-1193Japan 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2023年第29卷第24期

页      面:3758-3769页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Esophagogastric junction cancer Perioperative therapy Neoadjuvant therapy Surgery Multidisciplinary treatment 

摘      要:Incidence rates for esophagogastric junction cancer are rising rapidly worldwide possibly due to the economic development and demographic ***,increased attention has been paid to the prevention,diagnosis,and the treatment of esophagogastric junction *** there are discrepancies in the treatment strategy between Asian and Western countries,surgery remains the mainstay of treatment for esophagogastric junction *** developments of perioperative multidisciplinary treatment may lead to better therapeutic effect,higher complete resection rate,and better control of the residual diseases,thus result in prolonged *** this review,we will focus on the treatment of locally advanced resectable esophagogastric junction cancer,and discuss the current status and future perspectives of the perioperative treatment including chemotherapy,radiation therapy,and immunotherapy,as well as the surgical *** understanding of the latest treatment strategy and future overlook may enable to standardize and individualize the treatment for esophagogastric junction cancer,thus leading to better prognosis for those patients.

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