Extended Corey-Chaykovsky reactions:transformation of 2-hydroxychalcones to benzannulated 2,8-dioxabicyclo[3.2.1]octanes and 2,3-dihydrobenzofurans

作     者：Alexander A.Fadeev Anton S.Makarov Olga A.Ivanova Maxim G.Uchuskin Igor V.Trushkov 

作者机构：Department of ChemistryPerm State UniversityBukireva 15Perm 614990Russian Federation Department of ChemistryM.V.Lomonosov Moscow State UniversityLeninskie Gory 1-3Moscow 119991Russian Federation N.D.Zelinsky Institute of Organic ChemistryLeninsky pr.47Moscow 119334Russian Federation. D.Rogachev National Medical Research Center of Pediatric HematologyOncology and ImmunologySamory Mashela 1Moscow 117997Russian Federation 

出 版 物：《Organic Chemistry Frontiers》 (有机化学前沿（英文）)

年 卷 期：2022年第9卷第3期

页      面：737-744页

核心收录：

学科分类：07[理学] 070304[理学-物理化学(含∶化学物理)] 0703[理学-化学] 

基　　金：We thank the Russian Science Foundation(Grant 21-73-20095)for support of this work. 

主　　题：octane donor 

摘      要：We report the divergent synthesis of benzannulated 2,8-dioxabicyclo[3.2.1]octanes and 2,3-dihydrobenzofurans using the concept of extended Corey-Chaykovsky reactions.With this concept,2-hydroxychalcones were treated with the Corey ylide providing highly reactive donor-acceptor cyclopropanes that were introduced in a one pot manner for further transformations.