Evaluation of optic nerve head vessels density changes after phacoemulsification cataract surgery using optical coherence tomography angiography

作     者：Ze-Hui Zhu Yin-Ying Zhao Rui Zou Han Zou Jia-Yan Fang Ping-Jun Chang Yun-E Zhao 

作者机构：Eye Hospital and School of Ophthalmology and OptometryWenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina National Clinical Research Center for Ocular DiseasesWenzhou 325000Zhejiang ProvinceChina Eye Hospital of Wenzhou Medical University Hangzhou BranchHangzhou 310000Zhejiang ProvinceChina 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2023年第16卷第6期

页      面：884-890页

核心收录：

学科分类：08[工学] 081304[工学-建筑技术科学] 0805[工学-材料科学与工程（可授工学、理学学位）] 080502[工学-材料学] 0813[工学-建筑学] 

基　　金：Supported by Natural Science Foundation of Zhejiang Province (No.LQ19H120001) 

主　　题：phacoemulsification cataract optical coherence tomography angiography vessel density optic nerve head 

摘      要：·AIM:To evaluate optic nerve head(ONH)vessel density(VD)changes after cataract surgery using optical coherence tomography angiography(OCTA).·METHODS:This was a prospective observational ***-four eyes with mild/moderate cataracts were *** scans were obtained before and 3mo after cataract surgery using *** peripapillary capillary(RPC)density,all VD,large VD and retinal nerve fiber layer thickness(RNFLT)in total disc,inside disc,and different peripapillary sectors were assessed and *** quality score(QS),fundus photography grading and bestcorrected visual acuity(BCVA)were also collected,and correlation analyses were performed between VD change and these parameters.·RESULTS:Compared with baseline,both RPC and all VD increased in inside disc area 3mo postoperatively(from 47.5%±5.3%to 50.2%±3.7%,and from 57.87%±4.30%to 60.47%±3.10%,all P0.001),but no differences were observed in peripapillary ***,large VD increased from 5.63%±0.77%to 6.47%±0.72%in peripapillary ONH region(P0.001).RPC decreased in inferior and superior peripapillary ONH parts(P=0.019,0.001 respectively).There were obvious negative correlations between RPC change and large VD change in inside disc,superior-hemi,and inferior-hemi(r=-0.419,-0.370,and-0.439,P=0.017,0.044,and 0.015,respectively).No correlations were found between VD change and other parameters including QS change,fundus photography grading,postoperative BCVA,and postoperative peripapillary RNFLT.·CONCLUSION:RPC density and all VD in the inside disc ONH region increase 3mo after surgery in patients with mild to moderate *** obvious VD changes are found in peripapillary area postoperatively.