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Dentin-desensitizing biomaterials

作     者:Qihui Wang Jiayi Luan Zhilong Zhao Weihui Kong Congxiao Zhang Jianxun Ding Qihui Wang;Jiayi Luan;Zhilong Zhao;Weihui Kong;Congxiao Zhang;Jianxun Ding

作者机构:Department of Stomatologythe First Hospital of Jilin UniversityChangchun 130061China Key Laboratory of Polymer EcomaterialsChangchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China VIP Integrated DepartmentJilin Provincial Key Laboratory of Tooth Development and Bone RemodelingSchool and Hospital of StomatologyJilin UniversityChangchun 130021China 

出 版 物:《中国化学快报:英文版》 (Chinese Chemical Letters)

年 卷 期:2023年第34卷第8期

页      面:49-56页

核心收录:

学科分类:08[工学] 080502[工学-材料学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0703[理学-化学] 

基  金:This work was financially supported by the Special Program for Medical and Health Professionals of Jilin Province(No.JLSWSRCZX2021-085) the Achievement Transformation Fund of the First Hospital of Jilin University(Nos.JDYYZH-2102055 and JDYYZH-2102013) 

主  题:Biomaterial Dentin hypersensitivity Dentinal tubule closure Dental nerve blockade Regenerative medicine 

摘      要:Dentin hypersensitivity(DH)associated with dentinal tubule exposure is one of the most common causes of toothache with a rapid onset and short ***,filling repair,laser irradiation,crown therapy,and desensitizing toothpaste are standard clinical treatment strategies,but unsatisfactory treatment modalities are marked by long-term administration,poor dentinal tubule closure,microleakage,and the development of secondary *** improve the treatment efficiency of DH,numerous organic or inorganic biomaterials have been developed to relieve toothache and reverse the instability of *** are expected to participate in dental remineralization to achieve *** review discusses various biomaterials for DH therapy based on different desensitization mechanisms,including dentinal tubule closure and dental nerve blockade,and presents a perspective on the underlying future of dentin regeneration medicine for DH therapy.

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