A thermodynamic model showing that information recording can drive active ion transport

作     者：Xiang Zou Kun Song Minbiao Ji Lingzhao Min Liangfu Zhou Ying Mao Liang Chen Xiang Zou;Kun Song;Minbiao Ji;Lingzhao Min;Liangfu Zhou;Ying Mao;Liang Chen

作者机构：Department of NeurosurgeryNeurosurgical Institute of Fudan UniversityNational Center for Neurological DisordersHuashan HospitalFudan UniversityShanghai200040China Department of PhysicsFudan UniversityShanghai200433China State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain ScienceSchool of Basic Medical Sciences and Institutes of Brain ScienceFudan UniversityShanghai200040China 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2023年第8卷第5期

页      面：2058-2060页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 070203[理学-原子与分子物理] 0702[理学-物理学] 

基　　金：supported by National Natural Science Foundation of China (81970418,82272116) Shanghai Municipal Science and Technology Major Project (No.2018SHZDZX01) ZJLab Science and Technology Commission of Shanghai Municipality (Grant No.18JC1410403) MOE Frontiers Center for Brain Science Shanghai Municipal Health Commission Key Research Centre (2022ZZ01006). 

主　　题：recording maintained showing 

摘      要：Dear Editor,Ion gradients are characteristic features of a living cell that do not represent thermodynamic equilibrium.These unequilibrium status are maintained by various ion pumps such as Na-K-ATPase,which are known as the P-type ATPases.Working mechanism of Na-K-ATPase is described as Post-Albers cycle1(Fig.1a).However,the reaction scheme is non-Michaelis-Menten kinetics assembled from transient-state results,which can hardly be used to rebuild the real reaction cycle.