Organophosphate pesticides an emerging environmental contaminant: Pollution, toxicity, bioremediation progress, and remaining challenges

作     者：Himanshu Mali Chandni Shah B.H.Raghunandan Anil S.Prajapati Darshan H.Patel Ujjval Trivedi R.B.Subramanian Himanshu Mali;Chandni Shah;B.H.Raghunandan;Anil S.Prajapati;Darshan H.Patel;Ujjval Trivedi;R.B.Subramanian

作者机构：P.G.Department of BiosciencesUGC-Centre of Advanced StudiesSatellite CampusSardar Patel UniversitySardar Patel MaidanBakrol-Vadtal RoadBakrol 388315GujaratIndia Charotar Institute of Paramedical SciencesCharotar University of Science and Technology(CHARUSAT)Changa 388421GujaratIndia 

出 版 物：《Journal of Environmental Sciences》 (环境科学学报（英文版）)

年 卷 期：2023年第127卷第5期

页      面：234-250页

核心收录：

学科分类：0710[理学-生物学] 0832[工学-食品科学与工程（可授工学、农学学位）] 082803[工学-农业生物环境与能源工程] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 0828[工学-农业工程] 0815[工学-水利工程] 0836[工学-生物工程] 

基　　金：supported by Post Graduate Department of Biosciences Sardar Patel University.Himanshu Mali appreciates the financial support from CSIR-UGC NET-JRF/SRF fellowship for Ph.D.work(324997). 

主　　题：Organophosphorus compounds Toxicity Bioremediation Microorganisms Enzymes Biosensors 

摘      要：Organophosphates(OPs)are an integral part of modern agriculture;however,due to overexploitation,OPs pesticides residues are leaching and accumulating in the soil,and groundwater contaminated terrestrial and aquatic food webs.Acute exposure to OPs could produce toxicity in insects,plants,animals,and humans.OPs are known for covalent inhibition of acetylcholinesterase enzyme in pests and terrestrial/aquatic organisms,leading to nervous,respiratory,reproductive,and hepatic abnormalities.OPs pesticides also disrupt the growth-promoting machinery in plants by inhibiting key enzymes,permeability,and trans-cuticular diffusion,which is crucial for plant growth.Excessive use of OPs,directly/indirectly affecting human/environmental health,raise a thoughtful global concern.Developing a safe,reliable,economical,and eco-friendly methods for removing OPs pesticides from the environment is thus necessary.Bioremediation techniques coupled with microbes or microbial-biocatalysts are emerging as promising antidotes for OPs pesticides.Here,we comprehensively review the current scenario of OPs pollution,their toxicity(at a molecular level),and the recent advancements in biotechnology(modified biocatalytic systems)for detection,decontamination,and bioremediation of OP-pesticides in polluted environments.Furthermore,the review focuses on onsite applications of OPs degrading enzymes(immobilizations/biosensors/others),and it also highlights remaining challenges with future approaches.