骨关节炎中的“肠道菌群-关节轴”

作     者：魏捷 张余庆 David Hunter 曾超 雷光华 Jie Wei;Yuqing Zhang;David Hunter;Chao Zeng;Guanghua Lei

作者机构：Department of OrthopaedicsXiangya HospitalCentral South UniversityChangsha 410008China Health Management CenterXiangya HospitalCentral South UniversityChangsha 410008China Department of Epidemiology and Health StatisticsXiangya School of Public HealthCentral South UniversityChangsha 410008China Hunan Key Laboratory of Joint Degeneration and InjuryChangsha 410008China Division of RheumatologyAllergyand ImmunologyDepartment of MedicineMassachusetts General HospitalHarvard Medical SchoolBoston 02114USA The Mongan InstituteMassachusetts General HospitalHarvard Medical SchoolBoston 02114USA Sydney Musculoskeletal HealthKolling InstituteUniversity of Sydney and Rheumatology DepartmentRoyal North Shore HospitalSydney 2065Australia National Clinical Research Center for Geriatric DisordersXiangya HospitalCentral South UniversityChangsha 410008China 

出 版 物：《Science Bulletin》 (科学通报（英文版）)

年 卷 期：2023年第68卷第8期

页      面：759-762页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：supported by the National Key Research and Development Plan(2022YFC3601900 and 2022YFC2505500) the National Natural Science Foundation of China(U21A20352) the Project Program of National Clinical Research Center for Geriatric Disorders(2021LNJJ06) the Natural Science Foundation of Hunan Province(2022JJ20100)。 

主　　题：骨关节炎 肠道菌群 关节轴 

摘      要：Osteoarthritis(OA),the most common joint disorder,was reported to affect 7%of the global population,and the number of people with OA has increased by almost 50%from 1990 to 2019[1].OA can occur in almost any moveable joint;however,the most commonly affected joints are the knee,hip,and hand.Pain,swelling,and stiffness are the most common clinical symptoms.