Multi‐vital on‐skin optoelectronic biosensor for assessing regional tissue hemodynamics

作     者：Ming Xin Tong Yu Yongchang Jiang Ruowen Tao Jiean Li Feng Ran Tangsong Zhu Jinrong Huang Jing Zhang Jia‐Han Zhang Nan Hu Wei Wang Qiuhong Zhang Zhao Liu Xinran Wang Yi Shi Lijia Pan 

作者机构：Collaborative Innovation Center of Advanced MicrostructuresJiangsu Provincial Key Laboratory of Photonic and Electronic MaterialsSchool of Electronic Science and EngineeringNanjing UniversityNanjingChina Department of Vascular SurgeryNanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjingChina Department of Polymer Science and EngineeringSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjingChina 

出 版 物：《SmartMat》 (智能材料（英文）)

年 卷 期：2023年第4卷第3期

页      面：84-95页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 0802[工学-机械工程] 

基　　金：The National Key Research and Development program,Grant/Award Number:2021YFA1401103 China National Funds for Distinguished Young Scientists,Grant/Award Number:61825403 The National Natural Science Foundation of China,Grant/Award Numbers:61921005,61674078 

主　　题：biosensor cardiovascular disease flexible electronics skin inspired electronics 

摘      要：Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics *** example,peripheral arterial disease(PAD)is the third most prevalent cardiovascular disease,but the means of diagnosing and monitoring this disease are limited because the affected area is usually in the non‐pulsatile area away from the ***,we report on an ultrathin and ultralight multi‐vital near‐infrared optoelectronic biosensor for the diagnosis and rehabilitation monitoring of regional tissue hemodynamics,which is suitable for mounting on the skin for long‐term *** device can simultaneously detect tissue oxygen saturation,heart rate,arterial blood oxygen,and tissue perfusion and shows potential for various hypoxia monitoring ***,the tissue hemodynamics detected by this device showed a highly accordance with the ankle‐brachial index and CT angiography obtained by traditional clinical ***,our design was able to accurately diagnose and effectively evaluate PAD patients before and after *** on‐skin optoelectronic biosensor shows potential in biological oxygen‐mediated behavior evaluation,injury‐state monitoring,PAD clinical diagnosis optimization,and after surgery care.