A study on the relationship between acute pancreatitis and apoptosis of the acinar cells

作     者：邵宏伟 

作者机构：Dept Surg.Tianjin Gener HospTianjin Med Univ Tianjin 300052 

出 版 物：《外科研究与新技术》 (Surgical Research and New Technique)

年 卷 期：2003年第2期

页      面：79-79页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：necrotic severity hemorrhagic moderate negatively labeling positively continuously until 

摘      要：Objective To investigate the relationship between the severity of acute pancreatitis and apoptosis of acinar cells. Methods The apoptotic ratio of acinar cells was measured in rat acute pancreatitis model by methods of in situ end labeling. Results There was almost no apoptotic acinar cells in the model of acute edematous pancreatitis. With the increase in the severity of the pancreatitis apoptotic cells were more and more common until to the kte stage of hemorrhageic and necrotic pancreatitis when the apoptotic ratio of acinar cells dwindled,meanwhile the necrotic acinar cell increased continuously. Conclusion In acute simple edematous pancreatitis apoptotic acinar cells is infrequently seen. In acute moderate hemorrhagic and necrotic pancreatitis the ratio is correlated positively with the severity of pancreatitis. In the late stage the ratio was correlated negatively with the severity of pancreatitis. 3 refs,3 figs,2 tabs.